Breaking barriers through innovation

PharmFilm® and AdrenaVerse™ are designed to help patients overcome treatment barriers, revolutionize drug delivery, and diversify our pipeline.

Our core technologies

Pharmfilm Logo
PharmFilm:
The proven oral film platform

Aquestive was founded over 20 years ago on the promise of PharmFilm, our patented drug delivery method that enables precise oral delivery of almost any active pharmaceutical ingredient (API). PharmFilm isn’t just the technology behind two of our pipeline candidates—it’s also utilized by our strategic licensees who commercialize millions of doses of PharmFilm every year.

AdrenaVerse logo
AdrenaVerse:
Transforming epinephrine delivery

The AdrenaVerse™ platform contains a library of over 20 epinephrine prodrugs that demonstrate control of absorption and conversion rates across a variety of dosage forms including lotions, creams, and ointments (LCOs) and delivery sites. The AdrenaVerse platform enables us to pursue a variety of allergy and dermatological indications.

Pharmfilm single strip
WHAT IS PHARMFILM®?

Pharmfilm Logo

PharmFilm® is a unique and versatile technology for high-performance drug delivery. A small, postage-stamp sized film is taken orally, allowing for fast absorption of the active ingredient without the need for water or liquids. All routes of administration allow for direct entry into the bloodstream, without needles, pills, or injections. PharmFilm strip packaging is resistant to water, extremely durable, and allows for on-the-go convenience.

1
Sublingual administration
Dissolves quickly for rapid uptake and onset of action
Sublingual administration
2
Buccal administration
Greater surface area and reduced salivation
Buccal administration
3
Lingual administration
Rapid disintegration, and controlled release
Lingual administration

PharmFilm® customization 
for companies

Every medicine is different, so Aquestive follows a drug-by-drug approach for harnessing film technology to optimize target product profiles and clinical improvement goals. Our formulation engineering team optimizes absorption using proprietary matrices, pH modifiers, and FDA-approved permeation enhancers to meet target product profiles.
Adaptable polymer matrix
Variety of flavors
Array of FDA-approved
permeation enhancers
Range of drug loads

With three routes of administration (buccal, sublingual, and lingual), PharmFilm offers unmatched flexibility for companies looking to differentiate their product and offer patients easy, convenient dosing.
AdrenaVerse logo
WHAT IS ADRENAVERSE?

AdrenaVerse: 
the next generation of epinephrine therapy

The AdrenaVerse™ platform contains a library of over 20 epinephrine prodrugs. We’re exploring their potential across a variety of dosage forms including lotions, creams, and ointments (LCOs) and delivery sites. The AdrenaVerse platform enables us to pursue a variety of allergy and dermatological indications.

AdrenaVerse is a proprietary prodrug platform that looks to address local epinephrine exposure without undesirable systemic exposure.

Multiple formulation options, including gels and creams
Potential across inflammatory and autoimmune conditions
Use of existing Aquestive manufacturing infrastructure
Patent protection to 2037 with additional patents pending

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Meet the people who lead Aquestive.

Visit the portal to view clinical trial data and posters.

View the status of product candidates and access clinical trial data.

View the most recent press releases.